MILESTONES + MEDIA
We want to know how glia help wire the brain.
The Ackerman lab uses both zebrafish and fruit fly model systems to determine how distinct glial cell populations (individually and collectively) instruct nervous system development, from synapses to circuits.
To determine how glia instruct neural circuit structure and function, we need specific ways to alter gene function within individual glial cell populations…
To assay how glia shape neural circuit connectivity within an environment as complex as the central nervous system, we need a way to clearly label subsets…
Plasticity is the capacity of neurons to undergo activity-dependent changes in structure and function. Too much plasticity at the wrong developmental stage can lead…
We ultimately want to understand how defects in glia-mediated circuit development impact locomotor behavior, from flies to fish to humans…
Genetics, genomics, and statistics- oh my!
Time for science :)