The Ackerman lab uses both zebrafish and fruit fly model systems to determine how distinct glial cell populations (individually and collectively) instruct nervous system development, from synapses to circuits.
To determine how glia instruct neural circuit structure and function, we need specific ways to alter gene function within individual glial cell populations…
To assay how glia shape neural circuit connectivity within an environment as complex as the central nervous system, we need a way to clearly label subsets…
Plasticity is the capacity of neurons to undergo activity-dependent changes in structure and function. Too much plasticity at the wrong developmental stage can lead…